Praesto AP+

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Praesto AP+(也被称为“Praesto AP Plus”)是我们最新一代的亲和层析树脂，使用批次乳化技术生产。它是基于第一代产品Praesto AP的碱性稳定蛋白A亲和树脂，其性能超过其前身。


Praesto AP+是专为临床试验材料的生产和商业生产而设计的，通过显著增加Praesto AP的流动特性，同时保持高性能的性能，如动态结合能力，CIP稳定性和重现性。

有关我们的Protein A填料的常见问题，请访问我们的FAQs页面。

Product PDF
Resin Selection
Packing Procedure

PRINCIPAL APPLICATIONS

  • Protein purification (20-500 kDa)
  • MAb Purification

REGULATORY APPROVALS

  • Manufactured under cGMP conditions

ADVANTAGES

  • Excellent binding capacity – approx. 50g IgG per L of resin (at 6 minutes residence time)
  • Excellent flow properties – Max flow velocity of 400cm/h (pressure drop of less than 1.5 bar)
  • Alkaline stable for over 100 hours exposure to 0.1 M NaOH
  • Robust and reliable packability
  • Secure, validated supply at short lead times

TYPICAL PACKAGING

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns
TYPICAL PHYSICAL & CHEMICAL CHARACTERISTICS:
Polymer StructureHighly cross linked agarose
AppearanceSpherical beads
Functional GroupProtein A
Particle Size – µm85 µm
Dynamic Binding Capacity (min.)- 6 minutes residence time50 hlgG/ml
Pressure/flow (min.) – at 3 bar in a 2.6 x 20 cm column (pressure-packed at 4 bar)500 cm/h
pH stability, CIP (short term)2 – 12
pH stability, working range3 – 10
Recommended Storage2 – 8 °C
Recommended Storage20% ethanol