Praesto SP90

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Praesto SP 是一种琼脂糖基质的强阳离子交换填料,用来纯化生物分子,包括蛋白质、肽和寡核苷酸。有三种粒径的填料可供选择 – 45μm65μm和90μm –  根据不同粒径来获得高分辨率、适度分辨率或者捕获阶段。

同时Purolite 还提供‘Jetting’工艺生产的均粒强阳离子交换填料,Jetted SP35

如您有更多相关的疑问,可点击FAQs获得更多相关信息。

PRINCIPAL APPLICATIONS

  • Protein purification (20-500 kDa)
  • MAb Purification

REGULATORY APPROVALS

  • Manufactured under cGMP conditions

ADVANTAGES

  • High productivity
  • High dynamic binding capacity
  • Enhanced pressure/flow performance
  • NaOH CIP stability for up to 20 cycles
  • Secure, validated supply and regulatory support

TYPICAL PACKAGING

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns
TYPICAL PHYSICAL & CHEMICAL CHARACTERISTICS: 
Polymer StructureHighly cross linked agarose 
AppearanceSpherical beads 
Functional GroupSulfopropyl 
Chemical stabilityAll commonly used aqueous buffers. 1M NaOH, 8M urea, 6M guanidine hydrochloride, 30% isopropanol and 70% ethanol 
AvoidOxidising agents, cationic detergents 
Ionic capacity – medium0.11 – 0.16 mmol H⁺/ml 
Ionic capacity – resin0.11 – 0.16 mmol/ml 
Particle Size – µm45µm 
Dynamic Binding Capacity (min.) – 6 minutes residence time80 lgG/ml 
Dynamic Binding Capacity (min.)- 3 minutes residence time80 hlgG/ml
Pressure/flow (min.) – at 3 bar in a 2.6 x 20 cm column (pressure-packed at 4 bar)200 cm/h 
pH stability, CIP (short term) 3 – 14
pH stability, working range 4 – 13
Recommended Storage4 – 30 °C 
Recommended Storage20% ethanol 
Recommended Storage0.2M sodium acetate