Praesto Jetted SP35

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Praesto Jetted SP35 是一种琼脂糖基质的强阳离子交换填料，用来纯化生物分子，包括蛋白质、肽和寡核苷酸。它使用‘Jetting’工艺生产，一种能够生产窄粒径分布的琼脂糖填料的专利方法

Purolite是第一个能够工业化规模生产均颗粒琼脂糖填料的供应商。

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Product PDF
Jetted IEX resins
Packing Procedure

PRINCIPAL APPLICATIONS

  • Protein purification (20-500 kDa)
  • MAb Purification

REGULATORY APPROVALS

  • Manufactured under cGMP conditions

ADVANTAGES

  • Uniform particle size
  • Enhanced productivity
  • High dynamic binding capacity
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact
  • Secure, validated supply and regulatory support

TYPICAL PACKAGING

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns
TYPICAL PHYSICAL & CHEMICAL CHARACTERISTICS: 
MatrixCross-linked agarose
Functional GroupCH2CH2CH2S03
Ionic Capacity, mmol/mL Resin0.11-0.16
Average Particle Size (d50ᵥ), μm35
Flow Velocity cm/h at 3 bar in a 2.6 x 20 cm Column (packed at 4 bar)> 150
Binding Capacity mg/mL Resin at 6’ Residence Time> 90 mg/ml lgG
Operating pH Stability (Short Term)pH 3-14
Operating pH Stability (Long-Term)pH 4-13
Working Temperature4-30°C
Chemical stabilityAll commonly used aqueous buffers, 1M NaOH, 8M urea, 6M guanidine hydrochloride, 30% isopropanol and 70% ethanol
AvoidOxidizing agents, cationic detergents
Storage20% ethanol, 0.2M sodium acetate, 4-30°C