Praesto APc

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Praesto APc是一种专为高效、低成本捕获MAb而设计的ProteinA 填料。它结合了良好的载量，卓越的压力/流量性能和20个周期NaOH CIP稳定性，满足生产PI和PII临床试验填料的一般要求。Praesto APc还可用于小型单克隆抗体的纯化、单克隆抗体的诊断纯化、工艺开发和临床前处理。

点击这里查看科学文献，将我们的Praesto AP填料与市场上的其他产品进行对比。由独立第三方完成，发表在杂志《 Chromatography A》上。

有关我们的Protein A填料的常见问题，请访问我们的FAQs页面。

Product PDF
Packing File
Protein A Resins
User Instruction

PRINCIPAL APPLICATIONS

  • Protein purification (20-500 kDa)
  • MAb Purification

REGULATORY APPROVALS

  • Manufactured under cGMP conditions

ADVANTAGES

  • High productivity
  • Alkaline stable
  • Very high dynamic binding capacity
  • Enhanced pressure/flow performance
  • Low protein A leaching
  • Secure, validated supply and regulatory support

TYPICAL PACKAGING

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns
TYPICAL PHYSICAL & CHEMICAL CHARACTERISTICS:
Polymer StructureHighly cross linked agarose
AppearanceSpherical beads
Functional GroupProtein A
Particle Size – µm85 µm
Dynamic Binding Capacity (min.)- 3 minutes residence time35 hlgG/ml
Pressure/flow (min.) – at 3 bar in a 2.6 x 20 cm column (pressure-packed at 4 bar)500 cm/h
pH stability, CIP (short term)2 – 12
pH stability, working range3 – 10
Recommended Storage2 – 8 °C
Recommended Storage20% ethanol