CNBR

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Praesto® CNBr填料为配体固定在琼脂糖层析基质上提供一个简单的解决方案，可以用来制作定制的亲和介质。这使得从研发到大规模的生物工艺生产柱的规模得以迅速扩大。同时Purolite 还可以通过‘Jetting’工艺生产满足客户定制的粒径，能够精确控制任何颗粒的大小。

利用溴化氰(CNBr)预活化基质是一种成熟、快速、常规的生物特异性配体偶联技术，用于亲和层析纯化介质。这种预活化化学的选择非常适合于研究、诊断和学术应用。

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Product PDF
CNBr Datasheet

PRINCIPAL APPLICATIONS

  • Protein purification (20-500 kDa)
  • Production of customized affinity chromatography media

REGULATORY APPROVALS

  • Manufactured under cGMP conditions

ADVANTAGES

  • High productivity
  • High capacity
  • Enhanced pressure/flow performance
  • Secure, validated supply and regulatory support

TYPICAL PACKAGING

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns
TYPICAL PHYSICAL & CHEMICAL CHARACTERISTICS: 
Polymer StructureHighly cross linked agarose 
AppearanceSpherical beads 
Functional GroupCNBr 
Chemical stabilityAfter coupling – All commonly used aqueous buffers, 2M NaOH, 8M urea, 6M guanidine HCl, 30% isopropanol, 70% ethanol, 30% acetonitrile and commonly used detergents 
Particle Size – µm45, 65, 90 µm 
Pressure/flow (min.) – at 3 bar in a 2.6 x 20 cm column (pressure-packed at 4 bar)200 cm/h 
pH stability, CIP (short term) 2 – 11
pH stability, working range 3 – 11
Recommended Storage2 – 8 °C 
Recommended Storage20% ethanol(after coupling)