Pure

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Praesto Pure 是一种琼脂糖基质的强阳离子交换填料,用以大规模纯化生物分子。它是亲和层析填料理想的基质,有三种粒径的填料可供选择 – 45μm,65μm和90μm –  根据不同粒径来获得高分辨率、适度分辨率或者捕获阶段。Praesto Pure也可以用作大分子生物分子如病毒和质粒的凝胶过滤。

PRINCIPAL APPLICATIONS

  • Protein purification (20-500 kDa)
  • MAb Purification

REGULATORY APPROVALS

  • Manufactured under cGMP conditions

ADVANTAGES

  • High productivity
  • High capacity
  • Enhanced pressure/flow performance
  • Secure, validated supply and regulatory support

TYPICAL PACKAGING

  • Bulk Resin
  • Production-Scale OPUS® Columns
  • OPUS® Robocolumns®
  • OPUS® MiniChrom Columns
  • HT Columns
TYPICAL PHYSICAL & CHEMICAL CHARACTERISTICS: 
Polymer StructureHighly cross linked agarose 
AppearanceSpherical beads 
Functional GroupNot functionalized
Chemical stabilityAll commonly used aqueous buffers, 2M NaOH, 8M urea, 6M guanidine HCl, 30% isopropanol, 70% ethanol, 30% acetonitrile and commonly used detergents 
Particle Size – µm45, 65, 90 µm 
Pressure/flow (min.) – at 3 bar in a 2.6 x 20 cm column (pressure-packed at 4 bar)200 cm/h 
Exclusion limit for globular proteins 10 7 Daltons 
pH stability, CIP (short term) 2 – 14
pH stability, working range 3 – 14
Recommended Storage4 – 30 °C 
Recommended Storage20% ethanol